Antonino Belfiore Selected Research

Estrogens (Estrogen)

9/2023	GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway.
11/2021	Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer-associated fibroblasts.
1/2020	Microenvironmental Determinants of Breast Cancer Metastasis: Focus on the Crucial Interplay Between Estrogen and Insulin/Insulin-Like Growth Factor Signaling.
12/2017	Recent views of heavy metals as possible risk factors and potential preventive and therapeutic agents in prostate cancer.
1/2017	Insulin Resistance: Any Role in the Changing Epidemiology of Thyroid Cancer?
1/2015	Novel Aspects Concerning the Functional Cross-Talk between the Insulin/IGF-I System and Estrogen Signaling in Cancer Cells.
10/2014	GPER1 is regulated by insulin in cancer cells and cancer-associated fibroblasts.
8/2012	New advances on the functional cross-talk between insulin-like growth factor-I and estrogen signaling in cancer.
9/2009	Role of cyclic AMP response element-binding protein in insulin-like growth factor-i receptor up-regulation by sex steroids in prostate cancer cells.
2/2009	Sex steroids upregulate the IGF-1R in prostate cancer cells through a nongenotropic pathway.

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Antonino Belfiore Research Topics

Disease

81	Neoplasms (Cancer) 01/2024 - 01/2002
30	Breast Neoplasms (Breast Cancer) 07/2023 - 06/2004
14	Neoplasm Metastasis (Metastasis) 11/2023 - 08/2004
10	Thyroid Neoplasms (Thyroid Cancer) 01/2023 - 01/2002
9	Inflammation (Inflammations) 01/2024 - 09/2012
9	Prostatic Neoplasms (Prostate Cancer) 12/2017 - 03/2005
8	Obesity 11/2023 - 08/2011
8	Urinary Bladder Neoplasms (Bladder Cancer) 03/2023 - 01/2012
5	Mesothelioma 03/2023 - 08/2016
5	Carcinoma (Carcinomatosis) 03/2023 - 07/2003
5	Papillary Thyroid Cancer 10/2022 - 07/2003
5	Colorectal Neoplasms (Colorectal Cancer) 03/2022 - 11/2017
5	Type 2 Diabetes Mellitus (MODY) 01/2022 - 10/2009
5	Carcinogenesis 11/2020 - 01/2012
5	Insulin Resistance 01/2017 - 10/2009
4	Triple Negative Breast Neoplasms 01/2024 - 11/2021
4	Hyperinsulinism (Hyperinsulinemia) 01/2022 - 10/2009
3	Leiomyosarcoma 03/2023 - 11/2002
3	Hyperthyroidism 01/2023 - 01/2020
3	Lung Neoplasms (Lung Cancer) 01/2022 - 03/2009
3	Graves Ophthalmopathy 03/2021 - 01/2020
3	Hypoxia (Hypoxemia) 08/2020 - 01/2013
2	Adenoma (Adenomas) 01/2024 - 03/2022
2	Graves Disease (Basedow Disease) 03/2021 - 06/2004
2	Lymphatic Metastasis 01/2019 - 08/2004
2	Glioblastoma (Glioblastoma Multiforme) 01/2019 - 01/2016
2	Non-alcoholic Fatty Liver Disease 11/2013 - 01/2012
2	Sarcoma (Soft Tissue Sarcoma) 01/2013 - 01/2013
2	Ewing Sarcoma (Sarcoma, Ewing) 01/2013 - 09/2012
1	medullary Thyroid cancer 11/2023

Drug/Important Bio-Agent (IBA)

31	Insulin (Novolin)FDA Link 11/2023 - 11/2002
24	Insulin ReceptorIBA 01/2023 - 01/2002
20	Protein Isoforms (Isoforms)IBA 01/2023 - 01/2002
17	Insulin-Like Growth Factor II (Somatomedin A)IBA 01/2018 - 01/2002
16	Insulin-Like Growth Factor I (IGF-1)IBA 02/2021 - 03/2005
16	IGF Type 1 Receptor (IGF 1 Receptor)IBA 01/2017 - 11/2002
13	Estrogen ReceptorsIBA 09/2023 - 09/2007
11	LigandsIBA 11/2023 - 08/2011
11	Estrogens (Estrogen)FDA Link 09/2023 - 09/2007
10	ProgranulinsIBA 03/2023 - 01/2015
9	Insulin-Like PeptidesIBA 11/2023 - 09/2007
8	GTP-Binding Proteins (G-Protein)IBA 09/2023 - 10/2014
8	Biomarkers (Surrogate Marker)IBA 12/2022 - 01/2012
8	Proteins (Proteins, Gene)FDA Link 11/2022 - 06/2003
8	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 01/2012
7	Somatomedin Receptors (Somatomedin Receptor)IBA 01/2021 - 09/2007
7	AndrogensIBA 12/2017 - 03/2005
6	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 12/2022 - 01/2015
6	Collagen ReceptorsIBA 01/2021 - 06/2015
5	MicroRNAs (MicroRNA)IBA 01/2024 - 01/2017
5	Discoidin Domain Receptor 1IBA 01/2021 - 06/2015
4	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 07/2023 - 06/2015
4	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2023 - 04/2014
4	Androgen Receptors (Androgen Receptor)IBA 04/2014 - 03/2005
3	Receptor for Advanced Glycation End ProductsIBA 11/2023 - 02/2021
3	AntibodiesIBA 01/2023 - 07/2003
3	Conditioned Culture MediaIBA 12/2022 - 10/2015
3	Antineoplastic Agents (Antineoplastics)IBA 01/2022 - 01/2017
3	ErbB Receptors (EGF Receptor)IBA 01/2022 - 03/2009
3	IntegrinsIBA 01/2019 - 01/2017
3	Hypoglycemic Agents (Hypoglycemics)IBA 11/2013 - 08/2011
2	RNA (Ribonucleic Acid)IBA 01/2024 - 11/2021
2	EphrinsIBA 07/2023 - 08/2011
2	Trastuzumab (Herceptin)FDA Link 06/2023 - 12/2022
2	Phosphotransferases (Kinase)IBA 03/2023 - 01/2012
2	EphA2 ReceptorIBA 03/2023 - 12/2022
2	Hormones (Hormone)IBA 01/2023 - 03/2020
2	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 03/2010
2	ChemokinesIBA 01/2022 - 11/2021
2	CytokinesIBA 11/2021 - 08/2020
2	Glucagon-Like Peptide 1 (GLP 1)IBA 08/2021 - 11/2013
2	Cisplatin (Platino)FDA LinkGeneric 11/2020 - 06/2016
2	Heavy MetalsIBA 05/2020 - 12/2017
2	MetalsIBA 05/2020 - 12/2017
2	Capecitabine (Xeloda)FDA Link 03/2020 - 01/2020
2	Bevacizumab (Avastin)FDA Link 01/2020 - 01/2019
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020 - 01/2020
2	EnzymesIBA 01/2019 - 07/2003
2	CollagenIBA 01/2018 - 01/2017
2	CopperIBA 12/2017 - 10/2015
2	Trace Elements (Biometals)IBA 12/2017 - 01/2017
2	ZincIBA 12/2017 - 01/2017
2	sortilinIBA 12/2017 - 01/2015
2	CateninsIBA 11/2017 - 01/2017
2	ThiazolidinedionesIBA 01/2017 - 11/2013
2	Therapeutic UsesIBA 06/2016 - 01/2013
2	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 04/2014 - 09/2009
2	Complementary DNA (cDNA)IBA 05/2012 - 10/2002
2	SteroidsIBA 09/2009 - 02/2009
1	Carboplatin (JM8)FDA LinkGeneric 01/2024
1	Carcinoembryonic AntigenIBA 11/2023
1	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 11/2023

Therapy/Procedure

35	Therapeutics 11/2023 - 11/2002
6	Drug Therapy (Chemotherapy) 01/2024 - 01/2013
4	Thyroidectomy 11/2023 - 01/2019
3	Mediterranean Diet 01/2024 - 01/2019
3	Glycemic Control 08/2021 - 11/2013
2	Lymph Node Excision (Lymph Node Dissection) 11/2023 - 10/2022
2	Immunotherapy 01/2022 - 01/2022
2	Castration 12/2017 - 01/2015